The halfway point between Downtown Kansas City, Missouri and Buffalo, New York is: Greenfield, IN. Find a place to meet halfway.

Embark on a captivating road trip from Downtown Kansas City to Buffalo, exploring jazz districts, art museums, zoos, national parks, and the majestic Niagara Falls. Uncover the best attractions and experiences along this 800-mile journey through the heartland of America.

Planning a road trip from Downtown Kansas City to Buffalo, NY? Learn about the cost breakdown for different routes, gas prices, tolls, distance, and time estimates in this detailed guide.

Embark on a road trip from Downtown Kansas City to Buffalo, comparing the scenic I-70/I-80 and I-65/I-90 routes. Discover drive times, distances, and must-see pit stops for a memorable journey!